Most submissions do not result in payment. See Program Rules for details.
The Bar: "Replicable and Defensible"
Strong submissions are not just ideas. They're replicable (a third party can rerun your analysis) and defensible (there's a plausible IP strategy and a clear clinical edge).
Invention Types We Like
De novo molecules
Novel chemotypes with credible binding hypothesis + property plan
Repurposing
New indications for existing drugs with strong mechanistic evidence
Biobetters
PK/PD improvements (half-life extension, reduced immunogenicity, better route)
Formulations / route innovation
Delivery strategy with measurable clinical benefit
Combinations
Rationale + quantified synergy and differentiation from standard-of-care
High-Value Claim Types
We're looking for inventions that map cleanly to patentable claim sets:
- 1Composition of matter: novel small molecules, chemotypes, stereoisomers, salts, polymorphs, deuterated analogs
- 2Prodrugs: linker/trigger concepts with clear, non-obvious benefit
- 3Method of use: new indication/population/dosing backed by computational evidence
- 4Formulations & route: SR/ER, depot, transdermal, inhaled, SC conversion
- 5Biologics / biobetters: Fc engineering (YTE/LS), multispecifics, half-life extension
What "Good" Looks Like (Checklist)
AI Disclosure (Required)
AI tools are allowed, but you must disclose them and document human inventive contribution (AI cannot be an inventor). Minimum requirements:
- Tools + versions (models, platforms, checkpoints)
- Prompt / output logs (with secrets redacted)
- Human contribution narrative: what you conceived/decided/validated
- Data provenance: what data was used, licenses, citations
What We Don't Accept
Ready to Submit?
Start the intake form or review the full program rules before proceeding.